A randomised cross-over pilot trial has tested how Active Iron compared against regular iron (ferrous sulphate).
The clinical pilot study was carried out on a sample of fasted healthy volunteers (as iron is best absorbed on an empty stomach) with n=9 in each group (28-day crossover). Those taking part took the iron whey-protein microspheres or traditional ferrous sulphate supplements with each containing a similar amount of iron – 25mg elemental iron.
Active Iron was compared with regular iron taken at the same dose. Active Iron showed 124% better absorption with maximal 112% ± 58% increase in blood iron compared to 50% ± 26% for regular ferrous sulphate (p=0.01).

Data from the pilot study also demonstrated Active Iron was 2 to 3 times better absorbed than the market leaders.

The simulated models the scientists also looked at were the effects on gastric and intestinal damage. Results showed that Active Iron led to the generation of significantly less reactive oxygen species and had better viability in gut epithelial cells.
The release of iron from Active Iron was also found to be better in the presence of the enzyme pancreatin. This digestive enzyme is released naturally by humans in the small intestine. No unfavourable side-effects were reported for Active Iron.
These results show that Active Iron helps to deliver iron to the part of the gut where it is best absorbed and is further helped along by digestive enzymes naturally present in our bodies.

Wang J et al. (2016) Novel iron-whey protein microbeads improve iron absorption in fasting adults. European Journal of Medical Research [ahead of print].
Wang J et al. (2016) Novel iron-whey protein microbeads improve iron absorption in fasting adults. European Journal of Medical Research [ahead of print].